Miriam Rossi

Professor of Chemistry on the Mary Landon Sague Chair
Miriam Rossi Headshot

Miriam Rossi went to Hunter College in New York and obtained her PhD from The Johns Hopkins University. Afterwards, before coming to Vassar College, she spent some time at the Institute for Cancer Research of the Fox Chase Cancer Center in Philadelphia. Her research is concerned with the relationship between the structure and function of molecules, particularly those having biological activity. These include natural plant products that show anti-tumor activity and others that are strong food antioxidants such as curcumin and resveratrol. The principal technique she uses is single crystal X-ray diffraction, and she is co-author of a leading text in this area. She is a member of the US National Committee on Crystallography and the International Union of Crystallography Commission on Education.

BA, CUNY Hunter College; MA, PhD, Johns Hopkins University
At Vassar since 1982


Bridge for Laboratory Sciences
Box 484

Research and Academic Interests

X-ray crystallography of biologically active compounds


CHEM 146 The Culture and Chemistry of Cuisine
STS 146 The Culture and Chemistry of Cuisine

Selected Publications

Miriam Rossi, Francesco Caruso, Lorraine Kwok, Grace Lee, Alessio Caruso, Fabio Gionfra, Elena Candelotti, Stuart L. Belli, Nora Molasky, Kathleen M. Raley-Susman, Stefano Leone, Tomáš Filipský, Daniela Tofani, Jens Pedersen, Sandra Incerpi: Protection by extra virgin olive oil against oxidative stress in vitro and in vivo. Chemical and biological studies on the health benefits due to a major component of the Mediterranean diet. PLoS ONE 12/2017; 12(12):e0189341., DOI:10.1371/journal.pone.0189341

Francesco Caruso, Sarah Paumier, Miriam Rossi: X‐ray crystal structure of embelin and its DFT scavenging of superoxide radical. Journal of Computational Chemistry 08/2017;, DOI:10.1002/jcc.24915

Alessio Caruso, Miriam Rossi, Christopher Gahn, Francesco Caruso: A structural and computational study of citrulline in biochemical reactions. Structural Chemistry 07/2017; 28(4)., DOI:10.1007/s11224-017-0996-x

Francesco Caruso, Riccardo Pettinari, Miriam Rossi, Elena Monti, Marzia Bruna Gariboldi, Fabio Marchetti, Claudio Pettinari, Alessio Caruso, Modukuri V. Ramani, Gottumukkala V. Subbaraju: The in vitro antitumor activity of arene-ruthenium(II) curcuminoid complexes improves when decreasing curcumin polarity. Journal of inorganic biochemistry 06/2016; 162., DOI:10.1016/j.jinorgbio.2016.06.002

Shaibal Banerjee, Saikat Sinha, Padmanava Pradhan, Alessio Caruso, Daniel Liebowitz, Damon Parrish, Miriam Rossi, Barbara Zajc: Regiospecifically fluorinated polycyclic aromatic hydrocarbons via Julia–Kocienski olefination and oxidative photocyclization. Effect of fluorine atom substitution on molecular shape. The Journal of Organic Chemistry 03/2016; 81(10)., DOI:10.1021/acs.joc.5b02580

Manasi Jiwrajka, Alexandra Phillips, Matt Butler, Miriam Rossi, Jennifer M. Pocock: The plant-derived chalcone 2,2′,5′-trihydroxychalcone provides neuroprotection against toll-like receptor 4 triggered inflammation in microglia. Oxidative medicine and cellular longevity 01/2016; 2016(3):1-10., DOI:10.1155/2016/6301712

Sully Espinoza, Pablo Arce, Enrique San-Martín, Luis Lemus, Juan Costamagna, Liliana Farías, Miriam Rossi, Francesco Caruso, Juan Guerrero: The crystal structure of mono- and di-nuclear copper(I) complexes with substituted triphenylphosphine ligands. Polyhedron 01/2015; 85:405-411., DOI:10.1016/j.poly.2014.08.055

Francesco Caruso, Miriam Rossi, Alessio Caruso: Correlation between DFT calculated and X-ray structures from CSD, for Cu(II) and Cu(I) coordination spheres when coordinated to four acyclic amine ligands. A reconsideration of copper(II) planarity. Journal of Coordination Chemistry 11/2014; 67(23-24):3932-3939., DOI:10.1080/00958972.2014.964222

Francesco Caruso, Elena Monti, Julian Matthews, Miriam Rossi, Marzia Bruna Gariboldi, Claudio Pettinari, Riccardo Pettinari, Fabio Marchetti: Synthesis, characterization, and antitumor activity of water-soluble (Arene)ruthenium(II) derivatives of 1,3-dimethyl-4-acylpyrazolon-5-ato ligands. First example of ru(arene)(ligand) antitumor species involving simultaneous Ru-N7(guanine) bonding and ligand intercalation to DNA. Inorganic Chemistry 03/2014; 53(7)., DOI:10.1021/ic403170y

Grants, Fellowships, Honors, Awards

Grant for ‘Progetti coerenti con il Tema di EXPO Milano 2015 “Nutrire il pianeta, Energia per la vita” CUP n. F83D15000160009’ from Regione Lazio, Italy (2015)

Fulbright Senior Scholar Award (2008)

The Mary Landon Sague Chair in Chemistry (2000)

Mid-Hudson ACS Texaco Research Award (1993)

In the Media


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Miriam Rossi
Karl Rabe
Miriam Rossi
Karl Rabe